Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: Evolution toward prospective theranostic approaches

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dc.contributor.authorBejarano, Julian
dc.contributor.authorNavarro-Marquez, Mario
dc.contributor.authorMorales-Zavala, Francisco
dc.contributor.authorMorales, Javier O.
dc.contributor.authorGarcia-Carvajal, Ivonne
dc.contributor.authorAraya-Fuentes, Eyleen
dc.contributor.authorFlores, Yvo
dc.contributor.authorVerdejo, Hugo E.
dc.contributor.authorCastro, Pablo F.
dc.contributor.authorLavandero, Sergio
dc.contributor.authorKogan, Marcelo J.
dc.date.accessioned2022-09-09T18:14:12Z
dc.date.available2022-09-09T18:14:12Z
dc.date.issued2018
dc.descriptionIndexación Scopuses
dc.description.abstractCardiovascular diseases are the leading cause of death worldwide. Despite preventive efforts, early detection of atherosclerosis, the common pathophysiological mechanism underlying cardiovascular diseases remains elusive, and overt coronary artery disease or myocardial infarction is often the first clinical manifestation. Nanoparticles represent a novel strategy for prevention, diagnosis, and treatment of atherosclerosis, and new multifunctional nanoparticles with combined diagnostic and therapeutic capacities hold the promise for theranostic approaches to this disease. This review focuses on the development of nanosystems for therapy and diagnosis of subclinical atherosclerosis, coronary artery disease, and myocardial infarction and the evolution of nanosystems as theranostic tools. We also discuss the use of nanoparticles in noninvasive imaging, targeted drug delivery, photothermal therapies together with the challenges faced by nanosystems during clinical translation. © Ivyspring International Publisher.es
dc.description.urihttps://www.thno.org/v08p4710.htm
dc.identifier.citationTheranostics Volume 8, Issue 17, Pages 4710 - 4732 2018es
dc.identifier.doi10.7150/thno.26284
dc.identifier.issn18387640
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/23827
dc.language.isoenes
dc.publisherIvyspring International Publisheres
dc.rights.licenseCC BY 4.0
dc.subjectAtherosclerotic Plaqueses
dc.subjectSodium Fluorideses
dc.subjectPositron Emission Tomographyes
dc.subjectCardiovascular diseaseses
dc.subjectMyocardial infarctiones
dc.subjectNanoparticleses
dc.subjectTheranosticses
dc.titleNanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: Evolution toward prospective theranostic approacheses
dc.typeArtículoes
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