Untargeted Metabolomics by Using UHPLC–ESI–MS/MS of an Extract Obtained with Ethyl Lactate Green Solvent from Salvia rosmarinus

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dc.contributor.authorCastañeta, Grover
dc.contributor.authorCifuentes, Nicolas
dc.contributor.authorSepulveda, Beatriz
dc.contributor.authorBárcenas Pérez, Daniela
dc.contributor.authorCheel, José
dc.contributor.authorAreche, Carlos
dc.date.accessioned2023-06-05T17:04:26Z
dc.date.available2023-06-05T17:04:26Z
dc.date.issued2022-11
dc.descriptionIndexación: Scopus.es
dc.description.abstractSalvia rosmarinus (Lamiaceae), previously known as Rosmarinus officinalis, is a plant cultivated worldwide, native to the Mediterranean region. Its leaves are traditionally used for cooking. This species possesses numerous biological activities, including antioxidant, antimicrobial, anticancer, anti-inflammatory, and hepatoprotective properties. These biological properties are due to the presence of phenolic compounds, including rosmarinic acid and phenolic diterpenoids, such as carnosic acid and carnosol. In this study, we investigated the chemical composition of a green extract obtained by maceration with ethyl lactate for the first time. Seventy-five compounds were tentatively identified by UHPLC–ESI–MS/MS, including six organic acids, six cinnamic acid derivatives, five fatty acids, eighteen flavonoids, and thirty-eight terpenoids. Thus, abietane-type diterpenoids from the ethyl lactate extract were the predominant diterpenoids in the Chilean S. rosmarinus species, in contrast to the Chinese species, in which labdane and isopimarane-type diterpenoids were found for the first time. Finally, our study confirms that the extraction of S. rosmarinus with green ethyl lactate as a solvent is efficient and sustainable for the identification of flavonoids, phenols, and terpenoids from leaves. © 2022 by the authors.es
dc.description.urihttps://www.mdpi.com/2297-8739/9/11/327
dc.identifier.citationSeparations, Volume 9, Issue 11, November 2022, Article number 327es
dc.identifier.doi10.3390/separations9110327
dc.identifier.issn2297-8739
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/50312
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseAtribución 4.0 Internacional (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectAbietanees
dc.subjectEnvironmentes
dc.subjectEthyl lactatees
dc.subjectGreen chemistryes
dc.subjectPhenolic compoundses
dc.subjectRosemaryes
dc.subjectTerpenoidses
dc.titleUntargeted Metabolomics by Using UHPLC–ESI–MS/MS of an Extract Obtained with Ethyl Lactate Green Solvent from Salvia rosmarinuses
dc.typeArtículoes
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