Assessment of redundancy, methodological and reporting quality, and potential discrepancies of results of systematic reviews of early mobilisation of critically ill adults: A meta-research protocol

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dc.contributor.authorGutierrez-Arias, Ruvistay
dc.contributor.authorPieper, Dawid
dc.contributor.authorNydahl, Peter
dc.contributor.authorGonzález-Seguel, Felipe
dc.contributor.authorJalil, Yorschua
dc.contributor.authorOliveros, Maria-Jose
dc.contributor.authorTorres-Castro, Rodrigo
dc.contributor.authorSeron, Pamela
dc.date.accessioned2023-10-23T02:11:26Z
dc.date.available2023-10-23T02:11:26Z
dc.date.issued2023-07
dc.descriptionINDEXACIÓN: SCOPUS.es
dc.description.abstractIntroduction Several systematic reviews (SRs) have been conducted to determine the effectiveness of early mobilisation in critically ill adults with heterogeneous methodology and results. Redundancy in conducting SRs, unclear justification when leading new SRs or updating, and discordant results of SRs on the same research question may generate research waste that makes it difficult for clinicians to keep up to date with the best available evidence. This meta-research aims to assess the redundancy, methodological and reporting quality, and potential reasons for discordance in the results reported by SRs conducted to determine the effectiveness of early mobilisation in critically ill adult patients. Methods and analysis A meta-research of early mobilisation SRs in critically ill adult patients will be conducted. A search of MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Cochrane Library, Epistemonikos and other search resources will be conducted. Two independent reviewers will perform study selection, data extraction and quality appraisal. Discrepancies will be resolved by consensus or a third reviewer. The redundancy of SRs will be assessed by the degree of overlap of primary studies. In addition, the justification for conducting new SRs will be evaluated with the 'Evidence-Based Research' framework. The methodological quality of the SRs will be assessed with the A MeaSurement Tool to Assess systematic Reviews 2 tool, and the quality of the reports through compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. To assess the potential reasons for discordance in the results of the SRs considering divergence in results and their interpretation. Ethics and dissemination As meta-research, this study does not involve the participation of people whose rights may be violated. However, this overview will be developed rigorously and systematically to achieve valid and reliable results. The findings of this meta-research study will be presented at conferences and published in a peer-reviewed journal related to rehabilitation, critical care or research methodology. Trial registration number osf.io/kxwq9. © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.es
dc.identifier.citationBMJ Open, Volume 13, Issue 720, July 2023, Article number e074615es
dc.identifier.doi10.1136/bmjopen-2023-074615
dc.identifier.issn20446055
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/53532
dc.language.isoenes
dc.publisherBMJ Publishing Groupes
dc.rights.licenseCC BY-NC 4.0 DEED Attribution-NonCommercial 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectintensive & critical carees
dc.subjectrehabilitation medicinees
dc.subjectstatistics & research methodses
dc.titleAssessment of redundancy, methodological and reporting quality, and potential discrepancies of results of systematic reviews of early mobilisation of critically ill adults: A meta-research protocoles
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