Contribution of autophagy to antiviral immunity

Vista sencilla de ítem
dc.contributor.authorRey-Jurado, Emma
dc.contributor.authorRiedel, Claudia A.
dc.contributor.authorGonzález, Pablo A.
dc.contributor.authorBueno, Susan M.
dc.contributor.authorKalergis, Alexis M.
dc.date.accessioned2023-06-08T16:28:57Z
dc.date.available2023-06-08T16:28:57Z
dc.date.issued2015-05
dc.descriptionIndexación: Scopuses
dc.description.abstractAlthough identified in the 1960's, interest in autophagy has significantly increased in the past decade with notable research efforts oriented at understanding as to how this multi-protein complex operates and is regulated. Autophagy is commonly defined as a "self-eating" process evolved by eukaryotic cells to recycle senescent organelles and expired proteins, which is significantly increased during cellular stress responses. In addition, autophagy can also play important roles during human diseases, such as cancer, neurodegenerative and autoimmune disorders. Furthermore, novel findings suggest that autophagy contributes to the host defense against microbial infections. In this article, we review the role of macroautophagy in antiviral immune responses and discuss molecular mechanisms evolved by viral pathogens to evade this process. A role for autophagy as an effector mechanism used both, by innate and adaptive immunity is also discussed. © 2015 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.es
dc.description.urihttps://febs-onlinelibrary-wiley-com.recursosbiblioteca.unab.cl/doi/full/10.1016/j.febslet.2015.07.047
dc.identifier.citationFEBS Letters Volume 589, Issue 22, Pages 3461 - 34703 May 2015es
dc.identifier.doi10.1016/j.febslet.2015.07.047
dc.identifier.issn0014-5793
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/50486
dc.language.isoenes
dc.publisherElsevier B.V.es
dc.rights.licenseAtribución 4.0 Internacional (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectAdaptive immunityes
dc.subjectAutophagyes
dc.subjectInnate immunityes
dc.subjectMacroautophagyes
dc.subjectViruses
dc.titleContribution of autophagy to antiviral immunityes
dc.typeArtículoes
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
FEBS Letters - 2015 - Rey-Jurado - Contribution of autophagy to antiviral immunity.pdf
Tamaño:
1.06 MB
Formato:
Adobe Portable Document Format
Descripción:
TEXTO EN INGLES
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
Fac.CV - Artículos de Revista