Synthesis, physicochemical and photophysical characterization of 4-(1-Pyrenyl)-Butyl-α-d-mannopyranoside

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dc.contributor.authorSandoval, C.
dc.contributor.authorArriagada, F.S.
dc.contributor.authorDe La Fuente, J.R.
dc.contributor.authorSanchez, S.A.
dc.contributor.authorMorales, J.
dc.contributor.authorPizarro, N.
dc.contributor.authorNonell, S.
dc.contributor.authorGunther, G.
dc.date.accessioned2017-08-18T18:37:13Z
dc.date.available2017-08-18T18:37:13Z
dc.date.issued2016-02
dc.descriptionIndexación: Web of Science; Scopus; Scielo.es_CL
dc.description.abstractGlycolipids are biomolecules composed of a lipid chain (lipophilic) and a monosaccharide or oligosaccharide as hydrophilic group. Their chemical structure and biological role make them undoubtedly good candidates for a large and continuously growing number of biotechnological applications. Mannose is a carbohydrate present on membrane glycolipids of a wide number of pathogenic microorganisms (bacteria, fungi, protozoa, and viruses) and specifically recognized by several lectins. We synthesized a mannose derivative linked through a short methylene chain to a pyrene moiety which behaves as a surfactant, able to aggregate, and retains the photophysical properties of pyrene: showing comparable absorption and emission spectra, having lower fluorescence quantum yield and the ability to form excimer, and finally the ability to produce O-2((1)Delta(g)) with high quantum yields. Thus, this novel molecule would open future applications for detection (fluorescence) or inactivation (singlet oxygen) of bacterial pathogens, viruses, tumor cells, or particular cells.es_CL
dc.description.urihttp://ref.scielo.org/pcn4dw
dc.identifier.citationJ. Braz. Chem. Soc. vol.27 no.2 São Paulo Feb. 2016es_CL
dc.identifier.issn0103-5053
dc.identifier.otherhttp://dx.doi.org/10.5935/0103-5053.20150306
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/3977
dc.language.isoenes_CL
dc.publisherSociedade Brasileira de Químicaes_CL
dc.subjectPyrenees_CL
dc.subjectMannosees_CL
dc.subjectExcimeres_CL
dc.subjectSinglet oxygenes_CL
dc.subjectMicelleses_CL
dc.titleSynthesis, physicochemical and photophysical characterization of 4-(1-Pyrenyl)-Butyl-α-d-mannopyranosidees_CL
dc.typeArtículoes_CL
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