Physical Activity, Gut Microbiota, and Genetic Background for Children and Adolescents with Autism Spectrum Disorder

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dc.contributor.authorPlaza-Diaz, Julio
dc.contributor.authorRadar, Ana Mei
dc.contributor.authorBaig, Aiman Tariq
dc.contributor.authorLeyba, Marcos Federico
dc.contributor.authorCostabel, Maria Macarena
dc.contributor.authorZavala-Crichton, Juan Pablo
dc.contributor.authorSanchez-Martinez, Javier
dc.contributor.authorMacKenzie, Alex E.
dc.contributor.authorSolis-Urra, Patricio
dc.date.accessioned2025-01-24T15:23:06Z
dc.date.available2025-01-24T15:23:06Z
dc.date.issued2022-12
dc.descriptionIndexación: Scopus
dc.description.abstractIt is estimated that one in 100 children worldwide has been diagnosed with autism spectrum disorder (ASD). Children with ASD frequently suffer from gut dysbiosis and gastrointestinal issues, findings which possibly play a role in the pathogenesis and/or severity of their condition. Physical activity may have a positive effect on the composition of the intestinal microbiota of healthy adults. However, the effect of exercise both on the gastrointestinal problems and intestinal microbiota (and thus possibly on ASD) itself in affected children is unknown. In terms of understanding the physiopathology and manifestations of ASD, analysis of the gut–brain axis holds some promise. Here, we discuss the physiopathology of ASD in terms of genetics and microbiota composition, and how physical activity may be a promising non-pharmaceutical approach to improve ASD-related symptoms. © 2022 by the authors.
dc.description.urihttps://www.mdpi.com/2227-9067/9/12/1834
dc.identifier.citationChildren. Volume 9, Issue 12. December 2022. Article number 1834
dc.identifier.doi10.3390/children9121834
dc.identifier.issn2227-9067
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/63265
dc.language.isoen
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)
dc.rights.licenseAttribution 4.0 International Deed (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAutism Spectrum Disorder
dc.subjectChildren
dc.subjectGenetics
dc.subjectIntestinal Microbiota
dc.subjectPhysical Activity
dc.titlePhysical Activity, Gut Microbiota, and Genetic Background for Children and Adolescents with Autism Spectrum Disorder
dc.typeArtículo
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