Xenopus laevis como bioindicador de exposición a disruptores endocrinos en la región de Chile central

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Fecha
2017
Profesor/a Guía
Facultad/escuela
Idioma
en
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Universidad Andrés Bello
Nombre de Curso
Licencia CC
Licencia CC
Resumen
Concentrations of contaminants that act as endocrine disruptors (e.g. persistent organic compounds, heavy metals among others) are quantified in sediments, water and animal tissue in Chile. This type of compounds lead to reproductive, thyroid or adrenal failure in vertebrates, wich may in the future contribute to population decline. Finding those chemicals in different compartments of the environment suggests persistence, involuntary release or clandestine use of such substances, which have a potential risk for the conservation of the aquatic habitats in the mediterranean hotspot in central Chile. The results of this study revealed that the effects that those pollutants have on organismas have been less accessed in South American countries, being the reproductive topic mostly studied. In addition, in this study, the introduced species, Xenopus laevis (African clawed frog), revealed biological alterations, such as vitellogenin induction and decreased testosterone in male frogs, gross body index and histological changes that could be linked to pollutantas that act as endocrine disruptors present in the environment. Also estrogenic and dioxine like activity have ben accesed in sediments where the frogs were captured and related to some alterations observed in Xenopus laevis. Finally, AIC models were used with data from coverage and land use around the water bodies to reveal which of these models explain better the different variations found in the African clawed frog. In this study an invasive frog was evaluated, however different endemic species of these aquatic ecosystems may be facing a similar effect. This is relevant for the ecosystem in general, because it can indicate the ecosystem’s health where these animals live, also the potentially impact on wild species and human populations. This will be an important tool for future conservation strategies, identify vulnerable ecosystems from pollution and predict changes that may occur in the aquatic habitats in the mediterranean hotspot in central Chile.
Notas
Tesis (Doctor en Medicina de la Conservación)
This research project was conducted in accordance with Chilean law under permits N°1545/2014, N°7545/2014, N°8550/2014 of the Servicio Agrícola y Ganadero de Chile, and N°005/2014 of the Corporación Nacional Forestal de Chile.
Financial support was given by Universidad Andrés Bello Introduction to Research grant No. DI-592-14/I.
Palabras clave
Xenopus Laevis, Disruptores Endocrinos, Chile
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