Green synthesis of polysaccharides-based gold and silver nanoparticles and their promissory biological activity

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dc.contributor.authorGeraldo, DA
dc.contributor.authorNeedham, P
dc.contributor.authorChandia, N
dc.contributor.authorArratia-Perez, R
dc.contributor.authorMora, GC
dc.contributor.authorVillagra, NA
dc.date.accessioned2016-07-22T15:36:36Z
dc.date.available2016-07-22T15:36:36Z
dc.date.issued2016-06
dc.descriptionIndexación: Web of Sciencees
dc.description.abstractThis paper demonstrates a green approach for the synthesis of gold and silver nanoparticles using polysaccharides extracted from macroseaweed as reducing agents. The formation of Au-NPs and Ag-NPs was confirmed by UV-Vis spectroscopy and Transmission Electron Microscopy (TEM). TEM analysis of both polysaccharides-based metallic nanoparticles surprisingly showed that the type of the polysaccharides (alginate or carrageenan) not only influence the morphology and the sizes of the nanostructures but also avoid the aggregation of them. The biological activity of these eco-friendly metallic nanoparticles was tested on two Gram-negative pathogenic organisms such as Pseudomonas aeruginosa and Salmonella Typhimurium, showing similar activity than those ones prepared using the well-known inorganic reducing agent, sodium citrate (SC). Futhermore, hemolytic activity was also tested showing that the polysaccharides-based metallic nanoparticles (Ps-MNPs) were less cytotoxic than the corresponding gold and silver nanoparticles prepared using SC. These results strongly suggest that these Ps-MNPs could be used as antimicrobial agents for the treatment of bacterial infections.es
dc.description.urihttp://biointerfaceresearch.com/
dc.identifier.citationBiointerface Res. Appl. Chem., Volume 6, Issue 3, 2016es
dc.identifier.issn2069-5837
dc.identifier.urihttp://repositorio.unab.cl/xmlui/handle/ria/1139
dc.language.isoenes
dc.publisherBIOINTERFACE RESEARCH APPLIED CHEMISTRYes
dc.subjectLESSONIA-VADOSA PHAEOPHYTAes
dc.subjectSODIUM ALGINATEes
dc.subjectMETAL NANOPARTICLESes
dc.subjectBIOSYNTHESISes
dc.subjectSPECTROSCOPYes
dc.subjectRESISTANCEes
dc.subjectSUGARSes
dc.subjectALGAEes
dc.subjectACIDSes
dc.titleGreen synthesis of polysaccharides-based gold and silver nanoparticles and their promissory biological activityes
dc.typeArtículoes
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