Frailty Index as a Predictor of Mortality in Middle-Aged and Older People: A Prospective Analysis of Chilean Adults

dc.contributor.authorDiaz-Toro, Felipe
dc.contributor.authorNazar, Gabriela
dc.contributor.authorTroncoso, Claudia
dc.contributor.authorConcha-Cisternas, Yeny
dc.contributor.authorLeiva-Ordoñez, Ana Maria
dc.contributor.authorMartinez-Sanguinetti, Maria Adela
dc.contributor.authorParra-Soto, Solange
dc.contributor.authorLasserre-Laso, Nicole
dc.contributor.authorCigarroa, Igor
dc.contributor.authorMardones, Lorena
dc.contributor.authorVásquez-Gómez, Jaime
dc.contributor.authorPetermann-Rocha, Fanny
dc.contributor.authorDiaz-Martinez, Ximena
dc.contributor.authorCelis-Morales, Carlos
dc.date.accessioned2023-11-30T22:59:33Z
dc.date.available2023-11-30T22:59:33Z
dc.date.issued2023-01
dc.descriptionIndexación: Scopuses
dc.description.abstractWe aimed to investigate the association between frailty status and all-cause mortality in middle-aged and older people. We included 2661 individuals aged ≥ 35 from the Chilean National Health Survey 2009–2010. Mortality was determined through linkage with the Chilean Civil Registry and Identification. A 36-item frailty index (FI) was used to assess the frailty status. Associations between frailty status and all-cause mortality were assessed using Kaplan–Meier and Cox proportional hazard models adjusted for sociodemographic and lifestyle factors. A non-linear association was investigated using penalized cubic splines fitted in the Cox models. During an 8.9 median follow-up (interquartile range of 8.6–9.0), 308 individuals died (11.5%). Lower survival rates were observed in frail individuals compared to pre-frail and robust people (log-rank < 0.001). Compared with robust individuals, frail people had a higher mortality risk (HR: 2.35 [95% CI: 1.57 to 3.51]). Frail middle-aged individuals had a higher risk of dying independently of major risk factors. © 2023 by the authors.es
dc.description.urihttps://www.mdpi.com/1660-4601/20/2/1195
dc.identifier.citationInternational Journal of Environmental Research and Public Health Open Access Volume 20, Issue 2January 2023 Article number 1195es
dc.identifier.doi10.3390/ijerph20021195
dc.identifier.issn1661-7827
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/54261
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseAtribución 4.0 Internacional (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectChilees
dc.subjectFrailtyes
dc.subjectMiddle-agedes
dc.subjectMortalityes
dc.titleFrailty Index as a Predictor of Mortality in Middle-Aged and Older People: A Prospective Analysis of Chilean Adultses
dc.typeArtículoes
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