Intrahospital supervised exercise training improves survival rate amonghypertensive patients with COVID-19

dc.contributor.authorFernandez, Francisco
dc.contributor.authorVazquez-Muñoz, Manuel
dc.contributor.authorCanals, Andrea
dc.contributor.authorArce-Álvarez, Alexis
dc.contributor.authorSalazar-Ardiles, Camila
dc.contributor.authorAlvarez, Cristian
dc.contributor.authorRamirez-Campillo, Rodrigo
dc.contributor.authorIzquierdo, Mikelf
dc.contributor.authorAndrade, David C
dc.date.accessioned2023-03-23T20:10:12Z
dc.date.available2023-03-23T20:10:12Z
dc.date.issued2023-03
dc.descriptionIDEXACIÓN:SCOPUSes
dc.description.abstractAmong the people most affected by coronavirus disease 2019 (COVID-19) are those suffering from hypertension (HTN). However, pharmacological therapies for HTN are ineffective against COVID-19 progression and severity. It has been proposed that exercise training (EX) could be used as post-COVID treatment, which does not rule out the possible effects during hospitalization for COVID-19. Therefore, we aimed to determine the impact of supervised EX on HTN patients with COVID-19 during hospitalization. Among a total of 1,508 hospitalized patients with COVID-19 (confirmed by PCR), 439 subjects were classified as having HTN and were divided into two groups: EX (n = 201) and control (n = 238) groups. EX (3-4 times/wk during all hospitalizations) consisted of aerobic exercises (15-45 min; i.e., walking); breathing exercises (10-15 min) (i.e., diaphragmatic breathing, pursed-lip breathing, active abdominal contraction); and musculoskeletal exercises (8-10 sets of 12-15 repetitions/wk; lifting dumbbells, standing up and sitting, lumbar stabilization). Our data revealed that the EX (clinician: patient, 1:1 ratio) intervention was able to improve survival rates among controlled HTN patients with COVID-19 during their hospitalization when compared with the control group (chi-squared: 4.83; hazard ratio: 1.8; 95% CI: 1.117 to 2.899; P = 0.027). Multivariate logistic regression analysis revealed that EX was a prognostic marker (odds ratio: 0.449; 95% CI: 0.230-0.874; P = 0.018) along with sex and invasive and noninvasive mechanical ventilation. Our data showed that an intrahospital supervised EX program reduced the mortality rate among patients with HTN suffering from COVID-19 during their hospitalization.NEW & NOTEWORTHY In the present study, we found that exercise training improves the survival rate in hypertensive patients with COVID-19 during their hospitalization period. Our results provide strong evidence for the therapeutic efficacy of exercise training as a feasible approach to improving the outcomes of patients with COVID-19 who suffer from hypertension during their hospitalization.es
dc.identifier.citationJournal of applied physiology (Bethesda, Md. : 1985)Open AccessVolume 134, Issue 3, Pages 678 - 6841 March 2023es
dc.identifier.issn15221601
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/47848
dc.language.isoenes
dc.subjectCOVID-19; exercise training; hypertension; intrahospitales
dc.titleIntrahospital supervised exercise training improves survival rate amonghypertensive patients with COVID-19es
dc.typeArtículoes
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