Aortic pulse wave analysis and functional capacity of heart transplantation candidates: a pilot study

dc.contributor.authorAlcici-Moreira, Adriana Marques
dc.contributor.authorVitarelli, Marcela Oliveira
dc.contributor.authorVelloso, Tiago Abreu
dc.contributor.authorCarvalho-Ribeiro, Igor Antônio
dc.contributor.authorDario, Daniella Moura
dc.contributor.authorPolese, Janaine Cunha
dc.contributor.authorGuimarães, Hélio Penna
dc.contributor.authorPena, José Luiz Barros
dc.contributor.authorTuesta, Marcelo
dc.contributor.authorde Rezende, Bruno Almeida
dc.contributor.authorRodrigues-Machado, Maria da Glória
dc.date.accessioned2024-11-14T20:27:46Z
dc.date.available2024-11-14T20:27:46Z
dc.date.issued2024-12
dc.descriptionIndexación: Scopus.
dc.description.abstractWe compared cardiovascular parameters obtained with the Mobil-O-Graph and functional capacity assessed by the Duke Activity Status Index (DASI) before and after Heart Transplantation (HT) and also compared the cardiovascular parameters and the functional capacity of candidates for HT with a control group. Peripheral and central vascular pressures increased after surgery. Similar results were observed in cardiac output and pulse wave velocity. The significant increase in left ventricular ejection fraction (LVEF) postoperatively was not followed by an increase in the functional capacity. 24 candidates for HT and 24 controls were also compared. Functional capacity was significantly lower in the HT candidates compared to controls. Stroke volume, systolic, diastolic, and pulse pressure measured peripherally and centrally were lower in the HT candidates when compared to controls. Despite the significant increase in peripheral and central blood pressures after surgery, the patients were normotensive. The 143.85% increase in LVEF in the postoperative period was not able to positively affect functional capacity. Furthermore, the lower values of LVEF, systolic volume, central and peripheral arterial pressures in the candidates for HT are consistent with the characteristics signs of advanced heart failure, negatively impacting functional capacity, as observed by the lower DASI score. © The Author(s) 2024.
dc.description.urihttps://www-nature-com.recursosbiblioteca.unab.cl/articles/s41598-024-61152-w
dc.identifier.doi10.1038/s41598-024-61152-w
dc.identifier.issn2045-2322
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/62022
dc.language.isoen
dc.publisherScientific Reports, Volume 14, Issue 1December 2024 Article number 10504
dc.rights.licenseAttribution 4.0 International CC BY 4.0 Deed
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAdult
dc.subjectAorta
dc.subjectBlood Pressure
dc.subjectCardiac Output
dc.subjectFemale
dc.subjectHeart Failure
dc.subjectHeart Transplantation
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPilot Projects
dc.subjectPulse Wave Analysis
dc.subjectStroke Volume
dc.subjectVentricular Function
dc.subjectLeft
dc.titleAortic pulse wave analysis and functional capacity of heart transplantation candidates: a pilot study
dc.typeArtículo
Archivos
Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
s41598-024-61152-w.pdf
Tamaño:
1.1 MB
Formato:
Adobe Portable Document Format
Descripción:
TEXTO COMPLETO EN INGLÉS
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción: