Comparative analysis of Felixounavirus genomes including two new members of the genus that infect Salmonella infantis

dc.contributor.authorBarron-Montenegro, Rocío
dc.contributor.authorGarcía, Rodrigo
dc.contributor.authorDueñas, Fernando
dc.contributor.authorRivera, Dácil
dc.contributor.authorOpazo-Capurro, Andrés
dc.contributor.authorErickson, Stephen
dc.contributor.authorMoreno-Switt, Andrea I.
dc.date.accessioned2023-09-13T22:52:40Z
dc.date.available2023-09-13T22:52:40Z
dc.date.issued2021-07
dc.descriptionIndexación; Scopuses
dc.description.abstractSalmonella spp. is one of the most common foodborne pathogens worldwide; therefore, its control is highly relevant for the food industry. Phages of the Felixounavirus genus have the characteristic that one phage can infect a large number of different Salmonella serovars and, thus, are proposed as an alternative to antimicrobials in food production. Here, we describe two new members of the Felixounavirus genus named vB_Si_35FD and vB_Si_DR94, which can infect Salmonella Infantis. These new members were isolated and sequenced, and a subsequent comparative genomic analysis was conducted including 23 publicly available genomes of Felixounaviruses that infect Salmonella. The genomes of vB_Si_35FD and vB_Si_DR94 are 85,818 and 85,730 bp large and contain 129 and 125 coding sequences, respectively. The genomes did not show genes associated with virulence or antimicrobial resistance, which could be useful for candidates to use as biocontrol agents. Comparative genomics revealed that closely related Felixounavirus are found in distinct geographical locations and that this genus has a conserved genomic structure despite its worldwide distribution. Our study revealed a highly conserved structure of the phage genomes, and the two newly described phages could represent promising biocontrol candidates against Salmonella spp. from a genomic viewpoint. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.es
dc.description.urihttps://www.mdpi.com/2079-6382/10/7/806
dc.identifier.citationAntibiotics Volume 10, Issue 7July 2021 Article number 806es
dc.identifier.doi10.3390/antibiotics10070806
dc.identifier.issn2079-6382
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/53224
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseAtribución 4.0 Internacional (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectBacteriophageses
dc.subjectComparative genomicses
dc.subjectFelixounaviruses
dc.subjectGenomeses
dc.subjectSalmonella phageses
dc.subjectSalmonella sppes
dc.titleComparative analysis of Felixounavirus genomes including two new members of the genus that infect Salmonella infantises
dc.typeArtículoes
Archivos
Bloque original
Mostrando 1 - 1 de 1
Cargando...
Miniatura
Nombre:
Barron_R_Comparative_Analysis_of_Felixounavirus_Genomes_2021_Article.pdf
Tamaño:
4.92 MB
Formato:
Adobe Portable Document Format
Descripción:
TEXTO COMPLETO EN INGLES
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción: