Transfer of T6SSSPI-19from Salmonella Gallinarum to Salmonella Typhimurium Lacking T6SSSPI-6Complements its Colonization Defect in Mice

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dc.contributor.authorPezoa, David
dc.contributor.authorBlondel, Carlos J.
dc.contributor.authorAmaya, Fernando A.
dc.contributor.authorSantiviago, Carlos A.
dc.date.accessioned2024-11-04T16:08:32Z
dc.date.available2024-11-04T16:08:32Z
dc.date.issued2023-06
dc.descriptionIndexación: Scopus
dc.description.abstractSalmonella genus harbors five Type VI Secretion System (T6SS) gene clusters. The T6SS encoded in SPI-6 (T6SSSPI-6) contributes to Salmonella Typhimurium colonization of chickens and mice, while the T6SS encoded in SPI-19 (T6SSSPI-19) of Salmonella Gallinarum contributes to chicken colonization. Interestingly, the T6SSSPI-19 of Salmonella Gallinarum complemented the defect in chicken colonization of a Salmonella Typhimurium strain that lacks the T6SSSPI-6, suggesting that both T6SSs are interchangeable. Here we show that the transfer of Salmonella Gallinarum T6SSSPI-19 complemented the defect in mice colonization of a Salmonella Typhimurium ΔT6SSSPI-6 strain, indicating that both T6SSs are functionally redundant during host colonization. © 2023 David Pezoa et al., published by Sciendo.
dc.description.urihttps://sciendo.com/article/10.33073/pjm-2023-017
dc.identifier.citationPolish Journal of Microbiology. Volume 72, Issue 2, Pages 215 - 219. June 2023
dc.identifier.doi10.33073/pjm-2023-017
dc.identifier.issn1733-1331
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/61690
dc.language.isoen
dc.publisherSciendo
dc.rights.licenseCC BY-NC-ND 4.0 Attribution-NonCommercial-NoDerivatives 4.0 International Deed
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectColonization
dc.subjectMice
dc.subjectSalmonella Typhimurium
dc.subjectSPI-19
dc.subjectT6SS
dc.titleTransfer of T6SSSPI-19from Salmonella Gallinarum to Salmonella Typhimurium Lacking T6SSSPI-6Complements its Colonization Defect in Mice
dc.typeArtículo
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