Epithelial Transport in Disease: An Overview of Pathophysiology and Treatment
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Archivos
Fecha
2023-10
Profesor/a Guía
Facultad/escuela
Idioma
en
Título de la revista
ISSN de la revista
Título del volumen
Editor
MDPI
Nombre de Curso
Licencia CC
CC BY 4.0 DEED
Licencia CC
https://creativecommons.org/licenses/by/4.0/
Resumen
Epithelial transport is a multifaceted process crucial for maintaining normal physiological functions in the human body. This comprehensive review delves into the pathophysiological mechanisms underlying epithelial transport and its significance in disease pathogenesis. Beginning with an introduction to epithelial transport, it covers various forms, including ion, water, and nutrient transfer, followed by an exploration of the processes governing ion transport and hormonal regulation. The review then addresses genetic disorders, like cystic fibrosis and Bartter syndrome, that affect epithelial transport. Furthermore, it investigates the involvement of epithelial transport in the pathophysiology of conditions such as diarrhea, hypertension, and edema. Finally, the review analyzes the impact of renal disease on epithelial transport and highlights the potential for future research to uncover novel therapeutic interventions for conditions like cystic fibrosis, hypertension, and renal failure.
Notas
Indexación: Scopus.
Palabras clave
Epithelial transport, Genetic disorders, Hormonal regulation, Ion transport, Pathophysiology, Renal disease
Citación
Cells, Open Access Volume 12, Issue 20 October 2023 Article number 2455
DOI
10.3390/cells12202455