Marcadores sanguíneos para el diagnóstico de la enfermedad de Alzheimer
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Archivos
Fecha
2023
Profesor/a Guía
Facultad/escuela
Idioma
es
Título de la revista
ISSN de la revista
Título del volumen
Editor
Universidad Andrés Bello
Nombre de Curso
Licencia CC
Licencia CC
Resumen
Antecedentes: Los análisis de sangre permiten detectar y cuantificar diversos
componentes siendo un método rápido y sencillo, aportando en el diagnóstico de
diversas patologías o seguimiento de estas. Entre las enfermedades crónicas que
afectan a la población chilena de adultos mayores está la Enfermedad de Alzheimer
(EA), la cual es un trastorno neurodegenerativo crónico que afecta al sistema
nervioso central (SNC). Actualmente el diagnóstico en Chile consiste en aplicar tests
neuropsicológicos cuando las personas presentan manifestaciones clínicas, debido
a esto se busca comprobar si es eficaz la implementación de marcadores
sanguíneos para la realización del diagnóstico de la EA.
Hipótesis: La implementación de marcadores sanguíneos es eficaz para aportar en
el diagnóstico y/o seguimiento de la Enfermedad de Alzheimer sin someter al
paciente a procesos complejos y estresantes como lo son los métodos tradicionales.
Objetivos: Determinar la eficacia de los marcadores sanguíneos para diagnóstico
y seguimiento de la Enfermedad de Alzheimer.
Métodos: Se realizará una revisión sistemática de estudios, utilizando criterios de
inclusión-exclusión para refinar la búsqueda
Resultados/Conclusiones: Es posible la implementación de biomarcadores
sanguíneos para diagnóstico y seguimiento de la Enfermedad de Alzheimer, sin
embargo, el uso de solo un biomarcador no es suficiente.
Background: Blood tests allow the detection and quantification of various components, being a quick and simple method, contributing to the diagnosis of various pathologies or their monitoring. Among the chronic diseases that affect the Chilean elderly population is Alzheimer's Disease (AD), which is a chronic neurodegenerative disorder that affects the central nervous system (CNS). Currently, the diagnosis in Chile consists of applying neuropsychological tests when people present clinical manifestations. Due to this, the aim is to verify whether the implementation of blood markers is effective for the diagnosis of AD. Hypothesis: The implementation of blood markers is effective in contributing to the diagnosis and/or monitoring of Alzheimer's Disease without subjecting the patient to complex and stressful processes such as traditional methods. Objectives: Determine the effectiveness of blood markers for diagnosis and monitoring of Alzheimer's Disease. Methods: A systematic review of studies will be carried out, using inclusion exclusion criteria to refine the search. Results/Conclusions: The implementation of blood biomarkers for diagnosis and monitoring of Alzheimer's Disease is possible, however, the use of only one biomarker is not enough.
Background: Blood tests allow the detection and quantification of various components, being a quick and simple method, contributing to the diagnosis of various pathologies or their monitoring. Among the chronic diseases that affect the Chilean elderly population is Alzheimer's Disease (AD), which is a chronic neurodegenerative disorder that affects the central nervous system (CNS). Currently, the diagnosis in Chile consists of applying neuropsychological tests when people present clinical manifestations. Due to this, the aim is to verify whether the implementation of blood markers is effective for the diagnosis of AD. Hypothesis: The implementation of blood markers is effective in contributing to the diagnosis and/or monitoring of Alzheimer's Disease without subjecting the patient to complex and stressful processes such as traditional methods. Objectives: Determine the effectiveness of blood markers for diagnosis and monitoring of Alzheimer's Disease. Methods: A systematic review of studies will be carried out, using inclusion exclusion criteria to refine the search. Results/Conclusions: The implementation of blood biomarkers for diagnosis and monitoring of Alzheimer's Disease is possible, however, the use of only one biomarker is not enough.
Notas
Proyecto de seminario de investigación (Tecnólogo Médico)
Palabras clave
Marcadores Sanguíneos, Enfermedad de Alzheimer, Diagnóstico