Biomarkers in Oral Fluids as Diagnostic Tool for Psoriasis

Simple item page
dc.contributor.authorJiménez, C.
dc.contributor.authorBordagaray, M.
dc.contributor.authorVillarroel, J.
dc.contributor.authorFlores, T.
dc.contributor.authorBenadof, D.
dc.contributor.authorFernández, A.
dc.contributor.authorValenzuela, F.
dc.date.accessioned2022-05-11T20:21:13Z
dc.date.available2022-05-11T20:21:13Z
dc.date.issued2022-03
dc.descriptionIndexación: Scopus.es
dc.description.abstractPsoriasis is a prevalent worldwide chronic immuno-inflammatory skin disease with various variants and atypical cases. The use of biomarkers for the diagnosis of psoriasis can favor timely treatment and thus improve the quality of life of those affected. In general, the search for biomarkers in oral fluids is recommended as it is a non-invasive and fast technique. This narrative review aimed to identify biomarkers in gingival crevicular fluid (GCF) and saliva to diagnose psoriasis. To achieve this goal, we selected the available literature using the following MESH terms: “psoriasis”, “saliva” and “gingival crevicular fluid”. The studies analyzed for this review cover original research articles available in English. We found three full articles available for psoriasis biomarkers in GCF and ten articles available for psoriasis biomarkers in saliva. Studies showed that in the saliva of healthy individuals and those with psoriasis, there were differences in the levels of inflammatory cytokines, immunoglobulin A, and antioxidant biomarkers. In GCF, individuals with psoriasis showed higher levels of S100A8, IL-18 and sE-selectin in comparison to healthy individuals, independent of periodontal status. Despite these findings, more studies are required to determine an adequate panel of biomarkers to use in saliva or GCF for psoriasis.es
dc.description.urihttps://www.mdpi.com/2075-1729/12/4/501
dc.identifier.citationLife, Volume 12, Issue 4, April 2022, Article number 501es
dc.identifier.doi10.3390/life12040501
dc.identifier.issn2075-1729
dc.identifier.urihttps://repositorio.unab.cl/xmlui/handle/ria/22496
dc.language.isoenes
dc.publisherMDPIes
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttps://www.mdpi.com/journal/life/about
dc.subjectbiomarkerses
dc.subjectgingival crevicular fluides
dc.subjectpsoriasises
dc.subjectsalivaes
dc.subjectGingival Crevicular Fluides
dc.subjectNeutrophil Collagenasees
dc.subjectBiomarkerses
dc.titleBiomarkers in Oral Fluids as Diagnostic Tool for Psoriasises
dc.typeArtículoes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Jimenez_Biomarkers in Oral Fluids as Diagnostic Tool for Psoriasis.pdf
Size:
433.8 KB
Format:
Adobe Portable Document Format
Description:
TEXTO COMPLETO EN INGLES
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
FO - Artículos de Revista