Pharmacological treatment for challenging behavior in adults with intellectual disability: Systematic review and meta-analysis

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dc.contributor.authorCampos-Jara, R.
dc.contributor.authorMartínez-Salazar, C.
dc.contributor.authorCampos-Jara, Ch.
dc.contributor.authorFernándezx, J.
dc.contributor.authorMartínez-García, D.
dc.contributor.authorContreras-Osorio, F.
dc.date.accessioned2024-09-11T17:00:06Z
dc.date.available2024-09-11T17:00:06Z
dc.date.issued2023-01
dc.descriptionTEXTO COMPLETO EN INGLÉS
dc.description.abstractIntroduction Few evidence on the use of antipsychotics in people with intellectual disabilities and challenging behaviors, generates the need to develop studies that contribute to collect, compare and synthesize the available information. The present systematic review and meta-analysis aims to determine the clinical efficacy of antipsychotic medication in reducing critical episodes in this population. Methods We searched Web of Science, Scopus, EBSCO, Embase, and PubMed for randomized controlled trials of antipsychotic medication versus placebo. Preliminarily yielded 1354 abstracts and citations; six studies with 274 subjects met the inclusion criteria of studies with experimental design, longitudinal type, with pre- and post-intervention measurements. Results There is evidence for the use of psychotropic drugs in the acute management of challenging behaviors in patients with intellectual disability (SMD = −0.85; 95% CI = −1.69 to −0.01; p = 0.05). Conclusions Our results coincide with the recommendations on the efficacy of the use of antipsychotics. Although our study provides evidence, the limited number of studies included in this research does not allow us to obtain totally conclusive results, although it can be considered as a guide for future studies.
dc.description.urihttps://www-sciencedirect-com.recursosbiblioteca.unab.cl/science/article/pii/S1888989123000046
dc.identifier.citationRevista de Psiquiatría y Salud Mental, Available online 31 January 2023
dc.identifier.doihttps://doi.org/10.1016/j.rpsm.2023.01.003
dc.identifier.issn1888-9891
dc.identifier.urihttps://repositorio.unab.cl/handle/ria/60095
dc.language.isoen
dc.publisherSociedad Española de Psiquiatría and Sociedad Española de Psiquiatría Biológica
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International
dc.subjectIntellectual disability
dc.subjectChallenging behavior
dc.subjectPharmacological treatment
dc.titlePharmacological treatment for challenging behavior in adults with intellectual disability: Systematic review and meta-analysis
dc.typeArtículo
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