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A Novel Technique for Bulk-Fill Resin-Based Restorations: Achieving Function and Esthetics in Posterior Teeth
(Hindawi Limited, 2017) Durán Ojeda, Gerardo; Henríquez Gutiérrez, Ismael; Tisi, José Pablo; Báez Rosales, Abelardo
Advances in the mechanical properties of composite resins have allowed for their use in posterior teeth. Conventional resins have several problems associated with polymerization shrinkage stress. The development of "bulk-fill" resins has allowed for their use in single increments up to depths of 4 mm, with very low polymerization shrinkage stress. Nevertheless, differences in anatomy and the desire for optimal esthetics present unique difficulties. This article describes a step-by-step technique using flowable bulk-fill resin as a substitute for dentin in a single increment, together with a high-reflective-index resin to restore enamel and decrease clinical time, obtaining anatomically and esthetically acceptable results without detriment to the mechanical properties required to restore the functionality of the posterior teeth. © 2017 Gerardo Durán Ojeda et al.
A qualitative analysis of perceptions of orthodontists in Concepción about removable orthodontic appliances
(Universidad de Concepcion, 2017) Matthews, F.
Objective: To determine the utilization, attitudes and perceptions about removable orthodontic appliances (ROA) among a sample of Chilean orthodontists. Materials and methods: Data collection was performed using semi-structured interviews with 10 orthodontists from diverse professional backgrounds. The analysis was performed using the “Grounded Theory” methodology, using Atlas.ti v.6.0.15. Results: We interviewed four men and six women (31 to 75 years old), with 7 to 53 years of experience as dentists, and 1 to 10 years of experience as orthodontists. All orthodontists have experience in private practice, five in public service, and one in a military institution. One-hun-dred and thirty-three codes were grouped into seven categories identified as follows: perception of orthodontists, control over treatment, ROA characteristics, ROA indications and contraindications, patients’ attitude to ROA, selection of treatment, and ROA utilization. Conclusion: In the selection of ROA, different factors are involved, including the characteristics of the dentist, of the patient, and the social context. The key factor in the utilization of ROA is the perception of control over treatment.
A Step-by-Step Conservative Approach for CAD-CAM Laminate Veneers
(Hindawi Limited, 2017) Durán Ojeda, Gerardo; Henríquez Gutiérrez, Ismael; Guzmán Marusic, Álvaro; Báez Rosales, Abelardo; Tisi Lanchares, José Pablo
The use of CAD/CAM technology has allowed the fabrication of ceramic restorations efficiently and with predictable results. Lithium disilicate is a type of glass ceramic material that can be used for the elaboration of laminate veneers, being monolithic restorations which require characterization through a covering ceramic in order to achieve acceptable esthetic results. The next case report shows a predictable clinical protocol for the rehabilitation of the anterior teeth through the preparation of CAD/CAM veneers (e.max CAD, Ivoclar Vivadent, Liechtenstein) which have been characterized by a nanofluorapatite ceramic (e.max Ceram, Ivoclar Vivadent, Liechtenstein) through the layering technique. © 2017 Gerardo Durán Ojeda et al.
Absceso subperióstico y síndrome del vértice orbitario. Complicación posterior a la extracción del tercer molar mandibular
(Sociedad Chilena de Otorrinolaringología, Medicina y Cirugía de Cabeza y Cuello, 2009-08) Salado R, Lupe; Alvarez S, Lupe; Brunetto M, Beatriz
Introducción: La diseminación de las infecciones que se extienden de dientes mandibulares y estructuras adyacentes hacia la órbita y tejido periorbitario son infrecuentes, pero graves ya que tienen el potencial de causar la pérdida de la visión. Objetivos: El propósito de este artículo es publicar un caso clínico muy interesante por lo infrecuente, y explicar a juicio de los autores las vías de diseminación de la infección, a su vez alertar a los diferentes especialistas involucrados sobre las severas consecuencias que pueden resultar tras la extracción de piezas dentales, como es la pérdida definitiva de la visión. Reporte del caso: Se trata de un paciente masculino de 43 años, sin antecedentes mórbidos relevantes, que fue enviado al Servicio Médico Legal para examen clínico forense con pérdida total de la visión del ojo derecho por atrofia óptica como complicación de un síndrome del vértice orbitario, luego de la exodoncia del tercer molar mandibular derecho. Conclusiones: Es fundamental el tratamiento oportuno y agresivo para detener la diseminación de una infección desde las estructuras adyacentes hacia la órbita. La comunicación efectiva interdisciplinaria entre los profesionales involucrados evita complicaciones de tipo médico-legales y secuelas definitivas al paciente.
Absence of gender perspective in medical education. Implications in female and LGBT+ patients, students and professionals
(Universidad de Antioquia, 2020) Valenzuela-Valenzuela, A.; Cartes-Velásquez, R.
Health is a state of complete well-being, where biological, sociocultural and psychosocial factors interact with each other; gender is one of them. Nowadays, it has been proven that differences between sexes and genders have effects on many diseases; these differences are not usually addressed in medical education. Some of the main consequences are the inadequate attention of patients and the existence of various types of discrimination within medical education. The following review will examine how the absence of gender perspective in health education has effects on female patients and medical students, and on LGBT+ patients and medical students. In conclusion, there have been improvements, both in the attention of patients as well as in medical education, but the efforts on the subject must continue, especially in initial training of medical professionals.
Advantages of ultrasound guidance for TMJ arthrocentesis and intra-articular injection: A narrative review
(Wroclaw University of Medicine, 2022-10) De Nordenflycht, Diego; de Souza Tesch, Ricardo
Ultrasound (US) is a widely available, low-cost, non-invasive, and safe medical imaging method that enables real-time observation. Ultrasound offers several advantages for dentomaxillofacial images, such as portability, the possibility of dynamic and repeated examinations, patient comfort, and availability. It is a useful tool for recognizing the temporomandibular joint (TMJ) structures and their involvement during the course of different pathological processes, such as articular disk displacement, joint effusion and cortical erosion. In addition to its diagnostic use, US has been proposed as an auxiliary tool in minimally invasive procedures for arthrogenic temporomandibular disorders (TMD) to achieve an accurate puncture, recognize joint spaces and reduce surgical trauma. While US is widely used for large joints to visualize internal structures and guide the injection, this technique has only recently gained popularity for the TMJ procedures. Hence, the literature on this topic is scarce. The present review describes the potential advantages and the clinical technique of US guidance for TMJ arthrocentesis and intra-articular injection (IAI). © 2022, Wroclaw University of Medicine. All rights reserved.
Aging and oral squamous cell carcinoma development: the role of cellular senescence
(2023-11-01) Niklander, S.; Aránguiz, P.; Faunes, F.
The gradual accumulation and inadequate renewal of senescent cells over time drive organismal aging. Senescent cells undergo altered gene expression and release inflammatory mediators collectively termed the senescence-associated secretory phenotype (SASP), which significantly contributes to a spectrum of age-related disorders, including cancer. In the context of carcinogenesis, the SASP produced by senescent cells has been implicated in the promotion of epithelial cancers, including oral squamous cell carcinoma (OSCC), the most common form of oral cancer. Senescent cells within the tumor microenvironment release factors that amplify the growth and invasiveness of neighboring cancer cells. Senotherapeutics, including senolytics and senomorphics, emerge as promising modalities to target senescent cells and their associated inflammatory factors, thereby opening novel avenues for augmenting the efficacy of cancer treatments. Here, we review the general aspects of cellular senescence, focusing on the relation between senescence-related inflammation with cancer development. We also analyze the available evidence linking cellular senescence with OSCC, highlighting possible clinical applications.
Alveolar soft-part sarcoma of the masseter and mandibular ramus: Report of a case and review of the literature
(Association for Dental Sciences of the Republic of China, 2018-03) Martínez, René; Niklander, Sven; Deichler, Javiera; Leissner, Oliver; Seguel, Heraldo; Esguep, Alfredo
Alveolar soft-part sarcomas are clinically and morphologically distinct soft-tissue sarcomas, with an unknown histogenesis. When the tumors affect the region of the head and neck, they are often located in the orbit and tongue. We report a case of an alveolar soft-part sarcoma in the left masseter of a 28-year-old female. The patient had chronic pain and paresthesia of her left lower lip. Panoramic radiography and computed tomography showed a well-delimited radiolucent mass in the left ramus. An incisional biopsy was performed, and the sample submitted for histopathological study. The tumor showed positive periodic acid-Schiff diastase-resistant granules. Immunohistochemically, the tumor cells were diffusely positive for myoglobin, and focally positive for actin and desmin. © 2018
An implant periapical lesion associated with presence of residual root fragments: Report of case treated with apicoectomy
(Scientific Publishers of India, 2018) Honorato, L.; Alves, N.; Trillos, V.
The present study reports a case of a periapical lesion in an implant placed in an alveolar ridge which presented a residual root fragment of a deciduous tooth. Patient attended a dental clinic because she wanted to replace the missing tooth with an implant. She reported having lost the temporary tooth for one year. The initial Cone-beam Computerised Tomography image showed an edentulous area in the #13 zone, and the presence of a fragment of the deciduous tooth. The small root fragment was removed and an implant 4.0 × 13 mm amplified was installed. Patient presented acute pain and inflammation at the implant site 20 d after the surgery when the implant was originally installed; the first periapical surgery was carried out. Four months after the first periapical surgery, in periapical x-ray a radiolucent lesion was observed surrounding the apical region of the implant with a dry sound under percussion. The second periapical surgery was carried out. Five months after the second periapical surgery, the presence of a fistula was observed clinically, while in X-ray a radiolucent lesion was observed in the apex of the implant. Implant-plasty was carried out, removing approximately 5 mm of the apical portion of the implant. This treatment was successful after 27 months' monitoring. © 2018, Scientific Publishers of India. All rights reserved.
Análisis de las Fracturas Mandibulares Causadas por Accidentes Laborales. Estudio Descriptivo Retrospectivo
(Universidad de La Frontera. Facultad de Medicina, 2015-08) Gonzalez Mora, L. E.; Vargas Farren, I.; Pedemonte Trewhela, C.; Canales Trkovic, M.; Sáez Salas, F.; Verdugo-Avello, F.
El objetivo de este estudio fue evaluar la tendencia de los pacientes con fracturas mandibulares asociados a accidentes laborales. Se realizó un estudio descriptivo retrospectivo en todos los casos de fracturas mandibulares que asistieron al servicio de cirugía maxilofacial del Hospital Clínico Mutual de Seguridad C.Ch.C., Santiago de Chile en un periodo de 4 años (enero 2009 - diciembre 2012). Todas las fracturas mandibulares fueron consignadas. La información fue recopilada a través de revisión de fichas clínicas electrónicas. Entre los años 2009 al 2012 se presentaron un total de 74 pacientes incluidos en el estudio con 102 rasgos de fracturas mandibulares. La fractura más común fue la de cóndilo mandibular (35 pacientes). Se observó una tasa de complicaciones del 8%. Los resultados mostrados en este estudio están en línea con la literatura y el análisis de este reporte provee información para el diseño de planes de prevención de riesgos, especialmente para desarrollar medidas de protección facial. Nivel de Evidencia: Tipo II. Estudio descriptivo.
Analysis of the Anatomical and Dimensional Variations of the Nasopalatine Canal by Cone Beam Computed Tomography
(Universidad de la Frontera, 2023-06) Godoy, Iván E.; Valenzuela, Kimberly A.; Arce, Cecilia P.; Arqueros, Marcelo R.; Rodríguez, Macarena C.; Niklander, Sven E.; Meléndez, Patricio A.
Anatomical knowledge of the nasopalatine canal (PNC) is essential for performing surgeries in the anterior sector of the maxilla and thus anticipating possible complications. The objective of this work is to evaluate and determine the anatomical and dimensional variations of the CNP according to sex, age and dental status. This cross-sectional study analyzed a total of 251 CBCT images obtained from the database of the Oral and Maxillofacial Imaging Service of the Faculty of Dentistry of the Andrés Bello University, Viña del Mar, Chile. To evaluate the statistical association between CNP variations with sex, age and dental status, the Student's T test, chi-square and ANOVA (p<0.5) were performed. The CNP showed variability in terms of morphology and dimensions. The most predominant shape of the PNC was cylindrical (65.33 %) and the most frequent shape of the canal curvature in the sagittal plane was straight inclined (54.98 %). The mean length was 10.92 ± 2.82 mm, being greater in men (p<0.01). The most frequent anatomical variation in the coronal plane was the single channel type (57.76 %). The effect of sex on the distance between the anterior wall of the PNC and the buccal crest of the maxilla was not significant (p>0.05). In addition, a significant difference was detected between the dental state and the dimension of the vestibular table in relation to the CNP (p<0.01). CNP variations should be considered to avoid potential complications during surgical procedures. © 2023, Universidad de la Frontera. All rights reserved.
Antibacterial Effect of Luma apiculata (DC.) Burret Extracts in Clinically Important Bacteria
(International Journal of Microbiology, 2019) Araya-Contreras, Tiare; Veas, Rhonda; Escobar, Carlos A.; Machuca, Pamela; Bittner, Mauricio
Nosocomial infections caused by bacteria are one of the main public health problems. Moreover, the resistance to antibiotics by these bacteria makes it necessary to find new treatments to fight them. Objective. To evaluate the antibacterial activity of Luma apiculata (DC.) Burret extracts on bacteria of clinical importance. Materials and Methods. In this study, extracts were obtained at room temperature by successive extraction of L. apiculata leaves, flowers, and branches and treated separately with solvents of ascending polarity (i.e., hexane, methylene dichloride, ethyl acetate, ethanol, methanol, and water) to extract the compounds depending on their polarity. Then, the extract's antibacterial activity was tested against Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus, Enterococcus sp, Acinetobacter baumanii, Pseudomonas aeruginosa, and Escherichia coli. Results. The hexane extract of L. apiculata leaves resulted to be active against all bacteria tested. Among them, S. aureus showed to be the more susceptible, showing a minimum inhibitory concentration (MIC) of 120 μg/ml. In addition, a growth curve was performed, and colonies were counted. A decrease in bacterial growth was observed when the hexane extract of L. apiculata leaves was added. Besides, the hexane extracts of L. apiculata flowers resulted to be active against all Gram-positive tested bacteria. However, at higher concentrations, this extract resulted inactive for the Gram-negative bacteria tested. The hexane extract of L. apiculata branches resulted to be inactive in all cases. The extracts obtained treating separately leaves, flowers, or branches with solvents of major polarity than the hexane in a successive extraction of ascending polarity methodology resulted also to be inactive as an antimicrobial against all bacteria tested. Discussion/Conclusion. The hexane extract of L. apiculata leaves showed the lower MIC against S. aureus when compared with extracts obtained from other parts of the plant. The growth curve and the colonies count suggest a bacteriostatic activity of the L. apiculata leaves extract against Staphylococcus aureus.
Antimicrobial Photodynamic Therapy Combined with Photobiomodulation Therapy in Teeth with Asymptomatic Apical Periodontitis: A Case Series
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-10) Rubio, Francisco; Arnabat-Domínguez, Josep; Sans-Serramitjana, Eulàlia; Saa, Camila; Grzech-Leśniak, Kinga; Betancourt, Pablo
Introduction: Apical periodontitis (AP) is an inflammatory disease of the periapical tissues that is often asymptomatic and diagnosed through radiographic examination. A challenge in traditional endodontics is disinfection of the root canal system (RCS), which anatomically presents numerous variations, often leading to persistent infections. Antimicrobial photodynamic therapy (aPDT) and photobiomodulation therapy (PBMT) offer promising adjuncts, due to their antimicrobial and tissue-healing properties. Objective: The aim of this article was to report five cases of teeth with pulp necrosis and asymptomatic apical periodontitis (AAP) treated with aPDT and PBMT protocols. Materials and Methods: Five cases of pulp necrosis and AAP were treated with conventional endodontic therapy supplemented with aPDT and PBMT. The treatment protocol included chemomechanical preparation (CMP), aPDT using a 660 nm diode laser (DL) with methylene blue (MB) as a photosensitizer (5 min pre-irradiation time), and PBMT using a 940 nm DL. Treatment results were evaluated through cone-beam computed tomography (CBCT)-based evaluation over 1 year of clinical follow-up. Results: All cases showed significant bone regeneration and tissue healing, demonstrating the efficacy of the combination of aPDT and PBMT. Post-operative pain did not occur in any of the patients, suggesting a possible analgesic effect of PBMT. Conclusions: The combination of aPDT and PBMT in endodontic therapy promoted tissue recovery and improved the prognosis of AAP. Further research and randomized control trials are needed to optimize treatment protocols and evaluate the long-term effects.
Aplicación de biomateriales de base biológica, moléculas bioactivas e ingeniería de tejidos en cirugía plástica periodontal: Una revisión
(Sociedad de Periodoncia de Chile. Sociedad de Implantología Oral de Chile. Sociedad de Prótesis y Rehabilitación Oral de Chile., 2012) Durán Yaneth, J. C.; Alarcón, C.; Velásquez, D.
Objetivo: Describir, clasificar y discutir las indicaciones de los biomateriales de base biológica, moléculas bioactivas e ingeniería de tejidos que se están usando para el manejo de recesiones y aumento de encía en cirugía plástica periodontal. En esta revisión de la literatura, se utilizó una combinación de los términos de búsqueda específicos que consideraran los materiales en revisión, para el aumento de encía adherida, y el recubrimiento radicular. Materiales y Métodos: Se usaron las siguientes fuentes: Medline, Biblioteca Cochrane, y búsqueda manual de revistas específicas como el Journal of Periodontology, International Journal of Periodontics and Restorative Dentistry y Journal of Clinical Periodontology entre años 1985 y 2011. Se revisaron un total de 117 artículos y se seleccionaron 74 entre estudios clínicos controlados, estudios clínicos randomizados, reportes de casos y estudios en animales. Los artículos fueron revisados por los autores y aceptados por consenso para su discusión. Conclusiones: 1) Existe una serie de materiales que presentan gran potencial y podrían ser una alternativa viable a los injertos autógenos, pero se requiere más estudios a largo plazo. 2) Existe necesidad de estudios con la investigación de estos procedimientos en relación a resultados orientados a la estabilidad, seguridad y efectividad de los diferentes materiales existentes.
Articulación de fones en individuos clase esqueletal I,II y III
(CEFAC Slud y Educación, 2009) Villanueva, Pía; Morán Loreto, Daniel; Lizana, Maria; Palomino, Hernán M.
OBJETIVO: determinar los patrones de articulación de fones consonánticos en sujetos de habla española chilena clases I, II y III esqueletal; comparar las diferencias fonéticas que existan entre clases esqueletales. MÉTODOS: se seleccionaron 54 individuos que cumplían con los criterios de inclusión determinados mediante un examen clínico intraoral y a través del análisis de Ricketts, y se conformaron los grupos de estudio de pacientes clases esqueletales I, II y III. Se les realizó un examen fonoarticulatorio estandarizado para determinar los fones modificados y el patrón articulatorio compensatorio realizado. RESULTADOS: se observaron cambios en el punto de articulación de fones consonánticos en las tres clases esqueletales, con diferencias significativas en los grupos de fones anteriores y medios entre pacientes clases I y II, sólo en el grupo de los fones anteriores entre pacientes I y III. Entre pacientes clases II y III no se observaron diferencias significativas. Se reportan modificaciones y compensaciones cualitativamente distintas entre las clases esqueletales. CONCLUSIONES: en relación a pacientes clase I, los pacientes clase II o III, presentan distinto grado de modificación en el punto de articulación de fones consonánticos. Las diferencias observadas se relacionan con los patrones esqueletales propios de cada clase. ABSTRACT PURPOSE: to determine the consonant phonemes articulation patterns in Chilean skeletal class I, II and III Spanish speakers and compare their phonetic differences. METHODS: fifty-four skeletal class I, II and III subjects were selected, based on intraoral clinical examination and Ricketts cephalometric analysis, constituting the study groups. A standardized phonoarticulatory test was applied to each patient to determine the modified phonemes and their compensatory patterns. RESULTS: the findings indicate changes in articulation in all three groups. Significant differences were found in anterior and medium phonemes between skeletal class I and II and only in the anterior phonemes between skeletal class I and III. There were no significant differences between II and III skeletal groups. Qualitatively different modifications and compensations between skeletal classes are reported. CONCLUSION: different degree of modification in consonant phonemes articulation is shown in class II and III patients when compared to class I skeletal subjects. These differences are related to the skeletal patterns. Keywords: Malocclusion, Angle Class I; Malocclusion, Angle Class II; Malocclusion, Angle Class III; Speech; Phonetics
Artroscopía de la articulación temporomandibularTemporomandibular joint arthroscopy
(Clínica Las Conde, 2023) Ahumada, R.; de la Fuente, M.; Núñez, C.
La artroscopía de la articulación temporomandibular (ACTM), descrita por el Dr. Ohnishi en el año 1976, se ha posicionado como una alternativa terapéutica de gran utilidad en el tratamiento de las patologías de esta articulación dada su gran versatilidad y su baja morbilidad. Las patologías de la articulación temporomandibular (ATM) son complejas ya que su origen es multifactorial, generando desde trastornos inflamatorios articulares hasta patologías degenerativas con destrucción severa de la anatomía de la ATM. Los signos y síntomas suelen ser diversos, tales como dolor, alteraciones en la dinámica mandibular, trastornos oclusales, entre otros, afectando en forma importante la calidad de vida. Por lo antes descrito, no existe un tratamiento único y exclusivo para resolver estas patologías, sino que se ha establecido un tipo de tratamiento multimodal, siendo los tratamientos funcionales en conjunto con los tratamientos quirúrgicos, en los casos indicados, la mejor elección. La ACTM en estos últimos casos es útil, pues permite visualizar la articulación a través de un tratamiento mínimamente invasivo disminuyendo la morbilidad quirúrgica y siendo altamente versátil en tratar distintas patologías según su complejidad. El objetivo de este articulo es revisar el estado actual y los avances que ha tenido la ACTM como opción de tratamiento quirúrgico en las patologías de la ATM.
Asociación entre osteoporosis y periodontitis crónica
(Sociedad de Periodoncia de Chile. Sociedad de Implantología Oral de Chile. Sociedad de Prótesis y Rehabilitación Oral de Chile., 2016) Navarrete, Mariely; Carob, Juan C.; Pratob, Angelo; Secchib, Italo
La periodontitis crónica es una enfermedad inmunoinflamatoria causada por bacterias. Debido a los múltiples factores involucrados en la patogenia periodontal existen una serie de estudios sobre su probable asociación con diversas condiciones sistémicas, entre ellas osteoporosis. Esta es una enfermedad sistémica progresiva, caracterizada por una pérdida de masa ósea y deterioro de su microarquitectura, comprometiendo el hueso trabecular y cortical. El objetivo de este estudio fue identificar si existe asociación entre osteoporosis y periodontitis crónica, de acuerdo a la literatura especializada publicada hasta la fecha. Para tal efecto se realizó una búsqueda de la literatura en la base de datos Medline mediante su buscador PubMed. Se utilizó la siguiente estrategia de búsqueda: osteoporosis (Mesh) OR osteoporosis (TI) AND periodontal disease AND odds ratio OR osteoporosis (Mesh) OR osteoporosis (TI) AND periodontal disease AND association, seleccionando estudios en humanos, publicados en los últimos 10 años. Finalmente, 6 artículos fueron analizados. Estudios recientes entregan una fuerte evidencia de asociación entre osteoporosis y pérdida de inserción clínica en humanos. En función de estos resultados se puede concluir que existe una relación de riesgo entre la disminución de la densidad ósea esqueletal y la altura de la cresta ósea alveolar, sin embargo aún no es posible determinar una relación causal. Hasta la fecha esta asociación solo puede confirmarse en mujeres.
Assessment of cuspal deflection and volumetric shrinkage of different bulk fill composites using non-contact phase microscopy and micro-computed tomography
(Japanese Society for Dental Materials and Devices, 2018) Prager, M.; Pierce, M.; Atria, P.J.; Sampaio, C.; Cáceres, E.; Wolff, M.; Giannini, M.; Hirata, R.
The understanding of cuspal deflection and volumetric shrinkage of resin composites is necessary to assess and improve the placement techniques of resin-based materials. The aim of this study was to investigate the cuspal deflection and its relationship with volumetric polymerization shrinkage of different bulk-fill resin composites. The investigation was conducted using non-contact phase microscopy and micro-computed tomography. Thirty custom-milled aluminum blocks were fabricated for microscopy analysis and thirty-six tooth models with standardized Class I cavities were used for micro-computed tomography analysis. Results showed that high-viscosity composites present higher cuspal deflection compared to bulk-fill composites. The filler loading of resin composites seems to have an effect on cusp deflection, since the higher the filler content percentage, the higher the cusp deflection. On the other hand, it seems to have an opposite effect on volumetric shrinkage, since higher filler loadings produced lower volumetric shrinkage percentages. © 2018, Japanese Society for Dental Materials and Devices. All rights reserved.
Association of Periodontitis and Atopic Dermatitis with the Levels of IL-13, IL-31, and TSLP in the Gingival Crevicular Fluid
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-11) Jiménez, Constanza; Fernández, Javier; Aroca, Marcela; Bordagaray, María José; Pellegrini, Elizabeth; Contador, Javier; Hernández, Marcela; Valenzuela, Fernando; Fernández, Alejandra
Emerging epidemiological evidence links atopic dermatitis (AD) and periodontitis, although the mechanisms remain unclear. Th2-derived cytokines are key in the development of both diseases, and different gingival crevicular fluid (GCF) profiles among healthy and diseased subjects have been previously reported. This case–control study examined the GCF levels of interleukins (IL)-13, IL-31, and thymic stromal lymphopoietin (TSLP) in 29 subjects with moderate-to-severe AD and 33 controls. All subjects underwent comprehensive clinical and oral evaluations, followed by GCF collection. GCF levels of IL-13, IL-31, and TSLP were assessed using a multiplex-bead immunoassay. Demographic and periodontal parameters were similar among groups (p > 0.05). The GCF levels of IL-31 and TSLP were higher in AD subjects compared to controls (p < 0.05), whereas no significant differences in the GCF levels of IL-13 were noticed (p = 0.377). Moderate-to-severe AD was positively associated with the GCF levels of IL-31 and TSLP, whereas severe periodontitis was negatively associated with IL-31 (p < 0.05). The GCF levels of IL-13 showed no significant associations with either condition (p = 0.689). There was no significant interaction between AD and periodontitis for IL-31 (p < 0.869). These results suggest that AD and periodontitis independently influence the GCF levels of IL-31 in opposing ways, whereas AD alone influences the levels of TSLP.
Association of social factors and health conditions with capacity and performance
(UNIV SAOPAULO, 2022) Carvalho Arruda Barreto, M.; Cartes-Velásquez, R.; Campos, V.; Fortunato Araújo, L.; Sulyvan de Castro, S.
OBJECTIVE: Determine and measure the association of social factors and health conditions with worse capacity and performance levels. METHODS: Dependent variables consisted of performance and capacity; independent variables comprised age, gender, level of education, personal income, and health conditions. Means (95%CI) of performance and capacity were presented according to the independent variables. Generalized linear models, using a mutual adjustment for all variables considered statistically significant (p < 0.05), measured the associations between each exposure and outcomes. Study population included 12,265 individuals. RESULTS: Older women with lower education and income levels and with some health condition showed the worst performance and capacity. CONCLUSION: Results showed that the capacity and performance levels of the Chilean population changed according to social demographic characteristics and health conditions.

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